A New Preparation Method for Ophthalmic Drug Nanoparticles

A New Preparation Method for Ophthalmic Drug Nanoparticles

The eye is a small and complex organ that is separated from the rest of the body by multiple layers of biological barriers. Moreover, the internal ocular structures and tissues are protected from the external environment by the tight junctions of the corneal epithelium and the mucosal surface. The ophthalmic application of drugs is the primary route of administration for the treatment of variou...

A new precursor for preparation of magnetite (Fe3O4) nanoparticles

An anionic Fe(II) complex, (BMIM)4[Fe(CN)6] (where BMIM is 1-butyl-3-methylimidazolium), was synthesized in ionic liquid [BMIM][PF6] under reflux condition. The complex was characterized by elemental analysis and spectroscopic methods. The magnetite (Fe3O4) nanoparticles were prepared by the hydrothermal and solvothermal (in ionic liquid [BMIM][PF6]) methods from (BMIM)4[Fe(CN)6] as a precursor...

a novel method for preparation of solid lipid nanoparticles intended for drug delivery

Design of eudragit RL nanoparticles by nanoemulsion method as carriers for ophthalmic drug delivery of ketotifen fumarate

Objective(s): Ketotifen fumarate (KF) is a selective and noncompetitive histamine antagonist (H1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. The aim of this study was to formulate and improve an ophthalmic delivery system of KF.Ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtain...

a new precursor for preparation of magnetite (fe3o4) nanoparticles

an anionic fe(ii) complex, (bmim)4[fe(cn)6] (where bmim is 1-butyl-3-methylimidazolium), was synthesized in ionic liquid [bmim][pf6] under reflux condition. the complex was characterized by elemental analysis and spectroscopic methods. the magnetite (fe3o4) nanoparticles were prepared by the hydrothermal and solvothermal (in ionic liquid [bmim][pf6]) methods from (bmim)4[fe(cn)6] as a precursor...